Disease State: Rosacea
Rosacea is an extremely common multisystem inflammatory disorder that includes cutaneous and ocular manifestations. Apart from being disfiguring and socially embarrassing due to erythema, flushing, skin hypertrophy, and visible blood vessels, rosacea can be uncomfortable and painful. The range of possible treatments for cutaneous rosacea includes anti-inflammatory and antimicrobial agents, medications to reduce hyperemia, and vascular lasers and lights. Since research on more effective treatments for rosacea remains an active area of study, the development of a core outcome set for rosacea would be particularly useful for facilitating comparison of therapeutic modalities.
We aim to develop a core outcome set by (1) identifying all current outcomes from a systematic review of literature; (2) involving other stakeholder groups such as other clinicians, and regulators to participate in identifying additional outcomes; (3) conducting Delphi consensus exercises on the identified outcomes; (4) presenting all results from the Delphi exercises during a face-to-face (if possible) consensus meeting to vote and agree upon a core set of outcomes important for rosacea research.
Key Project Team Members
Todd V. Cartee
C3 Methods Partner
Murad Alam (firstname.lastname@example.org)
Iyengar S, Williamson PR, Schmitt J, Johannsen L, Maher IA, Sobanko JF, Cartee TV, Schlessinger D, Poon E, Alam M. Development of a core outcome set for clinical trials in rosacea: study protocol for a systematic review of the literature and identification of a core outcome set using a Delphi survey. Trials. 2016;17(1):429. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007842/
Updated on May 1, 2022